Studies and scientific information
Here you will find a compilation of the most important studies. For further studies, please check out our study database.
Meta-analysis: HAP effective in caries prevention
Fluoride-free hydroxyapatite toothpastes are not inferior to fluoride toothpastes in caries prevention.
Efficacy of HAP in caries prophylaxis
A systematic review with meta-analysis examined the efficacy of HAP. The result: HAP is as effective as fluoride in caries prophylaxis.
Toothpastes containing hydroxyapatite reduce dentin hypersensitivity
Hydroxyapatite forms a protective layer on the teeth, occluding exposed dentinal tubules and preventing dentine hypersensitivity.
Hydroxyapatite is a calcium-source
Hydroxyapatite delivers calcium to protect our teeth whilst simultaneously protecting them from acids.
Meta-analysis confirms: Dental care products containing hydroxyapatite reduce dentin hypersensitivity
An evaluation systematic analysis of 30 studies shows that hydroxyapatite is extremely effective in the case of reducing dentin hypersensitivity when compared with the other investigated active ingredients.
A clinical study shows that hydroxyapatite is effective in the prevention of dental cavities
A toothpaste containing hydroxyapatite is as effective in preventing cavities as a fluoride toothpaste. The study was conducted at 5 German university hospitals.
Deposition and formation of a protective layer with hydroxyapatite
Hydroxyapatite is deposited on the teeth, forming a protective layer against possible acid attacks.
Hydroxyapatite prevents bacteria from adhering to the surface of the teeth
Hydroxyapatite is highly effective in controlling the biofilm and has no effect on the ecological balance.
Healthy gums with hydroxyapatite toothpaste
A toothpaste containing hydroxyapatite reduces dental plaque to the same extend as a toothpaste containing amine and stannous fluoride.
A study shows that hydroxyapatite is effective in reducing dentin hypersensitivity
Hydroxyapatite occludes the dentinal tubules over a broad, deep area, preventing sensitive teeth.
Clinically proven: hydroxyapatite is effective in reducing dentin hypersensitivity
Hydroxyapatite is effective in reducing dentin hypersensitivity-even after a short time of application.
Other scientific publications
Significance of hydroxyapatite in oral care